About InVivoMAb anti-mouse CD96 The 6A6 monoclonal antibody reacts with CD96, also known as TACTILE (T cell activation increased late expression). CD96 is a type I transmembrane glycoprotein and member of the Ig superfamily. CD96 is expressed at low levels on resting NK cells and T cells and at high levels on activated NK and T cells. CD96 binds to its ligand, CD155 to mediate NK cell adhesion to target cells and cytotoxicity. CD96 has recently been identified as a novel target for cancer immunotherapy and has been shown to play a role in metastasis. InVivoMAb anti-mouse CD96 Specifications IsotypeRat IgG2a, λ Recommended Isotype Control(s)InVivoMAb rat IgG2a isotype control, anti-trinitrophenol Recommended Dilution BufferInVivoPure pH 7.0 Dilution Buffer FormulationPBS, pH 7.0 Contains no stabilizers or preservatives Endotoxin<2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay Purity>95% Determined by SDS-PAGE Sterility0.2 μm filtration ProductionPurified from cell culture supernatant in an animal-free facility PurificationProtein G Molecular Weight150 kDa StorageThe antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
