{"id":"48","post_author":null,"post_date":null,"post_date_gmt":null,"post_content":null,"post_title":"InVivoMAb polyclonal goat IgG","post_excerpt":"The polyclonal goat IgG is purified from goat serum. It is ideal for use as a non-reactive control IgG for goat IgG antibodies in most in vivo and in vitro applications.","post_status":"publish","comment_status":null,"ping_status":null,"post_password":null,"post_name":"invivomab-polyclonal-goat-igg-be0130","to_ping":null,"pinged":null,"post_modified":null,"post_modified_gmt":null,"post_content_filtered":null,"post_parent":null,"guid":null,"menu_order":null,"post_type":null,"post_mime_type":null,"comment_count":null,"filter":null,"sku":"BE0130","path":"\/product\/invivomab-polyclonal-goat-igg-be0130\/","image":"https:\/\/pneuma.bioxcell.com\/Media\/Products\/bioxcell-be0130-invivomab-polyclonal-goat-igg-polyclonal.png","brand_id":null,"brand_name":null,"brand_slug":null,"brand_description":null,"isotype":"Goat IgG","immunogen":null,"reported_applications":null,"aggregation":null,"formulation":"PBS, pH 7.0\nContains no stabilizers or preservatives","murine_pathogen_tests":"Mouse Norovirus: Negative\nMouse Parvovirus: Negative\nMouse Minute Virus: Negative\nMouse Hepatitis Virus: Negative\nReovirus Screen: Negative\nLymphocytic Choriomeningitis virus: Negative\nLactate Dehydrogenase-Elevating Virus: Negative\nMouse Rotavirus: Negative\nTheiler's Murine Encephalomyelitis: Negative\nEctromelia\/Mousepox Virus: Negative\nHantavirus: Negative\nPolyoma Virus: Negative\nMouse Adenovirus: Negative\nSendai Virus: Negative\nMycoplasma Pulmonis: Negative\nPneumonia Virus of Mice: Negative\nMouse Cytomegalovirus: Negative\nK Virus: Negative","human_pathogen_tests":null,"toxicity_test_results":null,"endotoxin":"<ul><li>\u22641EU\/mg (\u22640.001EU\/\u03bcg)<\/li><li>Determined by LAL gel clotting assay<\/li><\/ul>","purity":"<ul><li>\u226595%<\/li><li>Determined by SDS-PAGE<\/li><\/ul>","sterility":"0.2 \u03bcm filtration","production":"Purified from goat serum","purification":"Protein G","composition":null,"volume":null,"concentration":null,"molecular_weight":"150 kDa","storage":"The antibody solution should be stored at the stock concentration at 4\u00b0C. Do not freeze.","rrid":"AB_10949067","recommended_isotype_control":"","recommended_dilution_buffer":"<a href=\"\/product\/\">InVivoPure pH 7.0 Dilution Buffer<\/a>","clone":"Polyclonal","technical_data_sheet":"https:\/\/pneuma.bioxcell.com\/api\/v1\/products\/certificate-of-analysis\/BE0130\/0\/0\/0?apikey=23D50188E6F74755AFFBF95BD41B140B","western_blot_image":null,"new_product_image":null,"product_references":null,"display_pubmed_logo":null,"modified":"2026-03-21 02:10:05","active":"Y"}

InVivoMAb polyclonal goat IgG

Clone	Catalog #	Category
Polyclonal	BE0130

USD 172 - USD 4494

Technical Data Sheet

SDS Sheet

About InVivoMAb polyclonal goat IgG

The polyclonal goat IgG is purified from goat serum. It is ideal for use as a non-reactive control IgG for goat IgG antibodies in most in vivo and in vitro applications.

InVivoMAb polyclonal goat IgG Specifications

Isotype	Goat IgG
Recommended Dilution Buffer	InVivoPure pH 7.0 Dilution Buffer
Formulation	PBS, pH 7.0 Contains no stabilizers or preservatives
Endotoxin	≤1EU/mg (≤0.001EU/μg) Determined by LAL gel clotting assay
Purity	≥95% Determined by SDS-PAGE
Sterility	0.2 μm filtration
Production	Purified from goat serum
Purification	Protein G
RRID	AB_10949067
Molecular Weight	150 kDa
Storage	The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.

Application References

InVivoMAb polyclonal goat IgG (CLONE: Polyclonal)

Carretero, R., et al (2015). "Eosinophils orchestrate cancer rejection by normalizing tumor vessels and enhancing infiltration of CD8(+) T cells" Nat Immunol 16(6): 609-617. PubMed

Tumor-associated eosinophilia is frequently observed in cancer. However, despite numerous studies of patients with cancer and mouse models of cancer, it has remained uncertain if eosinophils contribute to tumor immunity or are mere bystander cells. Here we report that activated eosinophils were essential for tumor rejection in the presence of tumor-specific CD8(+) T cells. Tumor-homing eosinophils secreted chemoattractants that guided T cells into the tumor, which resulted in tumor eradication and survival. Activated eosinophils initiated substantial changes in the tumor microenvironment, including macrophage polarization and normalization of the tumor vasculature, which are known to promote tumor rejection. Thus, our study presents a new concept for eosinophils in cancer that may lead to novel therapeutic strategies.

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