About RecombiMAb human IgG4 S228P L235E P329G (SPLEPG) isotype control, anti-hen egg lysozyme This human IgG4 isotype control antibody reacts with hen egg lysozyme and has low or no specific binding to any human sample. The S228P substitution is included to prevent Fab-arm exchange. The P329G substitution combined with S228P and L235E substitutions has been shown to decrease effector functions by disrupting the Fc/Fcγ receptor interface. RecombiMAb human IgG4 S228P L235E P329G (SPLEPG) isotype control, anti-hen egg lysozyme Specifications IsotypeHuman IgG4 Recommended Dilution BufferInVivoPure pH 7.0 Dilution Buffer ImmunogenHen egg lysozyme (HEL) FormulationPBS, pH 7.0 Contains no stabilizers or preservatives Endotoxin<1EU/mg (<0.001EU/μg) Determined by LAL gel clotting assay Aggregation<5% Determined by SEC Purity>95% Determined by SDS-PAGE Sterility0.2 μm filtration ProductionPurified from CHO cell supernatant in an animal-free facility PurificationProtein A RRIDAB_2927522 Molecular Weight150 kDa StorageThe antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
