The Latest & Greatest From Bio X Cell Follow Us Research Type I IFN Exacerbates Disease in Tuberculosis Susceptible Mice by Inducing Neutrophil-mediated Lung Inflammation and NETosis January 1, 2021 Research Highlights Overcoming primary and acquired resistance to anti-PD-L1 therapy by induction and activation of tumor-residing cDC1s November 13, 2020 Research Highlights Neutrophil-induced ferroptosis promotes tumor necrosis in glioblastoma progression November 12, 2020 Research Highlights Immunocytokines are a promising immunotherapeutic approach against glioblastoma November 11, 2020 Research Highlights Endogenous DEL-1 restrains melanoma lung metastasis by limiting myeloid cell–associated lung inflammation November 9, 2020 Research Highlights Crizotinib-induced immunogenic cell death in non-small cell lung cancer November 5, 2020 Product MAb anti-human/monkey MDR-1 (CD243) (Clone UIC2) November 1, 2020 Research Highlights STAT5 promotes accessibility and is required for BATF-mediated plasticity at the Il9 locus October 30, 2020 Research Highlights Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer October 23, 2020 Research Highlights IL-20 antagonist suppresses PD-L1 expression and prolongs survival in pancreatic cancer models October 23, 2020 Research Highlights Decidual NK Cells Transfer Granulysin to Selectively Kill Bacteria in Trophoblasts October 15, 2020 Research Highlights Type I IFNs and CD8 T cells increase intestinal barrier permeability after chronic viral infection October 13, 2020 Research Highlights IκBα Nuclear Export Enables 4-1BB–Induced cRel Activation and IL-2 Production to Promote CD8 T Cell Immunity October 8, 2020 Research Highlights Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity October 1, 2020 Research Highlights Monocyte-derived dendritic cells link localized secretory IgA deficiency to adaptive immune activation in COPD September 30, 2020 Research Highlights Enhancing mucosal immunity by transient microbiota depletion September 24, 2020 Research Highlights Chronic activation of 4-1BB signaling induces granuloma development in tumor-draining lymph nodes that is detrimental to subsequent CD8+ T cell responses September 22, 2020 Product Highlights MAb anti-mouse CD96 Clone 3.3 September 21, 2020 Research Highlights TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy September 17, 2020 Research Highlights Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy September 15, 2020 Research Highlights Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine September 10, 2020 Research Highlights Serum HBsAg clearance has minimal impact on CD8+ T cell responses in mouse models of HBV infection September 3, 2020 Product Highlights Anti-mouse PD-1 (CD279) Clone 29F.1A12 September 1, 2020 Research Highlights PD-1 pathway regulates ILC2 metabolism and PD-1 agonist treatment ameliorates airway hyperreactivity September 1, 2020 Product Highlights MAb anti-human MUC1 (CD227) Clone C595 (NCRC48) August 31, 2020 Product Highlights Anti-mouse CD4 (Clone GK1.5) August 27, 2020 Research Highlights Tissue-resident memory Th17 cells maintain stable fungal commensalism in the oral mucosa August 27, 2020 Product Highlights Anti-mouse Ly6G/Ly6C (Gr-1) (Clone RB6-8C5) August 25, 2020 Research Highlights Tissue-resident memory T cell reactivation by diverse antigen-presenting cells imparts distinct functional responses August 25, 2020 Research Highlights Mouse CD163 deficiency strongly enhances experimental collagen-induced arthritis August 20, 2020 Research Highlights Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition August 18, 2020 Research Highlights In vivo microscopy reveals macrophage polarization locally promotes coherent microtubule dynamics in migrating cancer cells August 14, 2020 Research Highlights Imaging resident and recruited macrophage contribution to Wallerian degeneration August 11, 2020 Research Highlights Impacts of combining anti-PD-L1 immunotherapy and radiotherapy on the tumour immune microenvironment in a murine prostate cancer model July 28, 2020 Research Highlights Requirements for the differentiation of innate T-bethigh memory-phenotype CD4+ T lymphocytes under steady state July 23, 2020 Research Highlights Persistent Zika Virus Clinical Susceptibility despite Reduced Viral Burden in Mice with Expanded Virus-Specific CD8+ T Cells Primed by Recombinant Listeria monocytogenes July 21, 2020 Research Highlights Oncolytic virus-derived type I interferon restricts CAR T cell therapy July 16, 2020 Research Highlights Brg1 restrains the pro-inflammatory properties of ILC3s and modulates intestinal immunity July 14, 2020 Product Highlights MAb anti-human MAGEC2 (CT10) (Clone LX-CT10.5) July 13, 2020 Research Highlights Donor bone-marrow CXCR4+ Foxp3+ T-regulatory cells are essential for costimulation blockade-induced long-term survival of murine limb transplants July 8, 2020 Product 𝙄𝙣𝙑𝙞𝙫𝙤MAb anti-mouse NKG2D (CD314) (Clone CX5) July 1, 2020 Product Highlights Transcriptomics and proteomics reveal a cooperation between interferon and T-helper 17 cells in neuromyelitis optica June 25, 2020 Product Highlights MYC functions as a switch for natural killer cell-mediated immune surveillance of lymphoid malignancies June 25, 2020 Product Highlights Activation of JUN in fibroblasts promotes pro-fibrotic programme and modulates protective immunity June 23, 2020 Product Highlights Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer June 17, 2020 Product Highlights Contrast-enhanced ultrasound with sub-micron sized contrast agents detects insulitis in mouse models of type1 diabetes June 16, 2020 Product Anti-mouse CTLA-4 (CD152) June 11, 2020 Research Microbiota-derived short-chain fatty acids limit the anti-tumor effect of CTLA-4 blockade June 11, 2020 Product Highlights Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer June 9, 2020 Product Highlights Effective combinatorial immunotherapy for penile squamous cell carcinoma June 4, 2020 Product InVivoMAb anti-mouse/human/rat LRP1 (CD91) June 3, 2020 Product Highlights Deubiquitination of NLRP6 inflammasome by Cyld critically regulates intestinal inflammation June 2, 2020 Product Highlights Neutrophil extracellular traps released by neutrophils impair revascularization and vascular remodeling after stroke May 28, 2020 Product Highlights anlotinib alters tumor immune microenvironment by downregulating PD-L1 expression on vascular endothelial cells May 26, 2020 Product Highlights Hepatocyte mitochondria-derived danger signals directly activate hepatic stellate cells and drive progression of liver fibrosis May 20, 2020 Product Highlights Ly6cLo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation May 14, 2020 Product InVivoMAb anti-mouse TIGIT May 7, 2020 Product Highlights Blood-stage malaria parasites manipulate host innate immune responses through the induction of sFGL2 May 6, 2020 Product Highlights Collagen-binding IL-12 enhances tumour inflammation and drives the complete remission of established immunologically cold mouse tumours April 30, 2020 Research TIGIT limits immune pathology during viral infection April 9, 2020 Research FGL-1 is a major inhibitory receptor of LAG-3 and its blockade can potentiate anti-tumor T cell responses April 8, 2020 Product InVivoMAb anti-mouse FGL-1 April 7, 2020 Product InVivoMAb anti-rat/mouse CD71 (TfR1) March 9, 2020 Product InVivoMAb anti-mouse CD69 February 18, 2020 Research Targeting sphingolipid metabolism enhances cancer immunotherapy February 11, 2020 Product InVivoMAb anti-mouse CD71 (TfR1) (Clone: 8D3) January 21, 2020 Product Top Ten Antibodies in 2019 December 23, 2019 Research Skin resident neutrophils protect against MRSA infection December 12, 2019 Product InVivoMAb anti-mouse CD28 (Clone: D665) November 25, 2019 Research Targeted CD103+ CD8 T cell depletion prolongs the survival of diabetic mice November 6, 2019 Product InVivoMAb anti-human IL-9 (Clone: MH9A4) November 4, 2019 Research Optimizing anti-4-1BB agonistic antibodies for cancer immunotherapy September 20, 2019 Product Discover if IL-27 plays a role in your research September 3, 2019 Product Does type I collagen play a role in your research? July 22, 2019 Product Does TL1A-DR3 signaling play a role in your research? June 18, 2019 Research Prophylactic treatment with antagonistic anti-TNFα antibodies may improve outcomes of anti-PD-1 and anti-CTLA-4 combination cancer immunotherapy June 11, 2019 Product Deplete neutrophils in mice with InVivoMAb anti-mouse March 27, 2019 Research Activation of ILC2 expressed GITR ameliorates type 2 diabetes March 22, 2019 Product The FasL and the Furious – Introducing anti-mouse Fas ligand (CD178) March 5, 2019 Research Melanoma tumors use IFNγ mutations to fight anti-CTLA-4 immunotherapy March 2, 2019 Product How do I decide which anti-mouse PD-1 antibody is best for me? February 8, 2019 Research Oxygen sensing by T cells facilitates the establishment of cancer metastasis in the lung January 26, 2019 Product Bio X Cell’s Top 20 December 20, 2018 Research A Novel Immune Checkpoint Inhibitor Anti-NKG2A Antibody Promotes Anti-Tumor Immunity by Unleashing Both T and NK Cells December 13, 2018 Research Microbial Infection Induces Autoimmunity November 30, 2018 Research Anti-CD47 antibodies counter cardiovascular disease November 12, 2018 Research Blocking messages carried through brain lymphatic vessels curbs the development of multiple sclerosis October 25, 2018 Research Naïve T cells switch to one-carbon metabolism upon activation September 21, 2018 Research Microbiota-derived short-chain fatty acids promote Th1 cell IL-10 production to maintain intestinal homeostasis September 6, 2018 Research LIGHT-HVEM signaling protects against enteric bacterial infection August 23, 2018 Research The program for central memory T cell generation is preserved intrinsically in CD8 T cells. August 10, 2018 Research TIGIT blockade prevents NK cell exhaustion and elicits potent anti-tumor immunity July 20, 2018 Research Regulatory T cells use lymphotoxin beta receptor to migrate from tissues to lymph nodes July 10, 2018 Research CD40 stimulation drives T cell immunity in cancer July 1, 2018 Product Highlights Product Highlights January 1, 1970 Product Does SIRPα play a role in your research? January 1, 1970 Categories All Posts94Product20Product Highlights21Research53